Hypertrophic pulmonary osteo-arthropathy (Pierre Marie-Bamberger syndrome)
This is the combination of clubbing and thickening of periosteum (connective tissue lining of the bones) and synovium (lining of joints), and is often initially diagnosed as arthritis. It is commonly associated with lung cancer.
Primary HOA
Primary hypertrophic osteo-arthropathy is HPOA without signs of pulmonary disease.It is also known as the Touraine-Solente-Golé syndrome. This condition has been linked to mutations in the gene on the chromosome4 coding for the enzyme 15-hydroxyprostaglandin dehydrogenase (HPGD); this leads to decreased breakdown of prostaglandin E2.
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NOTE
Medicine is a tough and vast subject. The little knowledge we gather here and there may help us in future in a huge way. This blog is dedicated to those students who seem lost in the third year of medicine who are trying to study something .
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